Evaluation of histopathological features of Argas reflexus bite in pigeon

Iranian Journal of Veterinary Science and Technology

مقاله 4، دوره 6، شماره 2، فروردین 2014، صفحه 29-41   

نوع مقاله: Research Articles

شناسه دیجیتال (DOI): 10.22067/veterinary.v6i2.21042

نویسندگان

Maryam Gholizadeh^{* 1}؛ Mousa Tavassoli¹؛ Farid Rezaei²؛ Zahra Nikousefat²

¹Urmia University

²Razi University

چکیده

Argas reflexus is considered obligate blood feeder that may cause skin redness and local swelling. For histopathological evaluation of biting site, pigeons were used as natural host species in this study. Adult ticks were collected from Urmia, North-west of Iran and kept in a desiccator before their use in the experiment. Sixteen Pigeons were infested experimentally and were divided into 4 groups, euthanized after 30 min, 4, 24 and 48h for evaluation of histopathological changes in biting sites. Early histopathologic lesions due to time of infestation included edema, hemorrhagic foci, vascular congestion, necrosis and mild to severe inflammatory reaction in dermis. In late lesions, presence of micro abscess foci in dermis was prominent. This study well documented the different pathological changes of skin of pigeons with Argas reflexus. However, further study should be performed to evaluate allergic immune responses and pathological changes in other animal species including human.

کلیدواژه‌ها

Argas reflexus؛ Tick؛ Pigeon؛ histopathology

مراجع

Amosova, LI (1994). The ultrastructural characteristics of the histipathological changes at the site of attachment to the host body of larvae of the Ixodid tick Ixodes ricinus. Parasitology 28, 356-363.

 

Balashov, YUS and Grrigor’eva, LA (2002). Local histopathological changes of amniote skin by a feeding caused by a feeding tick (Acari: Ixodinae). Doklady biological sciences 385, 349-351.

 

Berenberug, JL; Ward, PA and Sonenshine, DE (1972). Tick-bite injury: Mediation by a complement-derived chemotictic chemotactic factor. Journal of Immunology 109, 451-456.

 

Bergman, DK; Palmer, MJ; Caimano, MJ; Radolf, JD and Wikel, SK (2000). Isolation and molecular cloning of a secreted immunosuppressant protein from Dermacentor andersoni salivary gland. Journal of Parasitology 86, 516–525.

 

Bessot, JC; Kopferschmitt, MC; deBlay, F; Dietemann, A; Nirrengarten, A and Hutt, N (1997). Chocs anaphylactiques apre`s morsure de tiques de pigeon (Argas reflexus): a propos de 12 cas. Revue Francxaise de_Allergologie etd_Immunologie Clinique 37, 431-7.

 

Bowman, AS and Sauer, JR (2004). Tick salivary glands: function, physiology and future. Parasitology 129, S67–S81.

 

Chastel, C; Bach-Hamba, D; Karabatsos, N; Bouattour, A; LeLay, G and LeGoff, F (1994). Tunis virus: a new Phlebovirus from Argas reflexus hermanni ticks in Tunes. Acta Virology 38, 285-289.

 

Cho, BK; Kang, H; Bang, D; Kim, SN; Hwang, S and Song, ES (1994). Tick bites in Korea. International Journal of Dermatology 33, 552-555.

 

Dautel, H; Kahl, O and Knulle, W (1991). The soft tick Argas reflexus (Acari: Argasidae) in urban environments and its medical significance in Berlin (West). Journal of Applied Entomology 11, 380-390.

 

Dautel, H and Knulle, W (1997). Life cycle and seasonal development of post-embryonic Argas reflexus (Acari: Argasidae) at two thermally different location in central Europe. Experimental and Applied Acarology l21, 697-712.

 

Dautel, H and Knulle, W (1998): The influence of physiological age of Argas reflexus larvae (Acari: Argasidae) and of temperature and photoperiod on induction and duration of diapause. Oecologia 113, 46-52.

 

Dautel, H; Scheurer, S and Kahl, O (1999). The pigeon tick (Argas reflexus): its biology, ecology, and epidemiological aspects. Zentbl Bakteriology 289, 745-753.

 

Dautel, H; Kahl, O; Scheurer, S and Kntille, W (1994). Seasonal activities of the pigeon tick Argas reflexus (Acari: Argasidae) in Berlin, Germany. Folia Parasitology 41, 155-160.

 

Demain, JG (2003). Papulary urticaria and things that Bite in the night. Current Allergy and Asthma Reports 3, 291-293.

 

DenHollander, N and Allen, JR (1985). Dermacentor variabilis: acquired resistance to ticks in BALB/c mice. Experimental Parasitology 59, 118–129.

 

Estrada-Pena, A and Jongejon, F (1999). Ticks feeding on humans: a review of records on human-biting Ixodidea with special reference to pathogen transmission. Experimental and Applied Acoralogy 23, 675-715.

 

Fisher, EJ; Jun-Mo, MD; Anne, MD and Lucky, W (2006). Multiple pruritic papula from Lone Star tick larvae bites. Archive of Dermatology 142, 491-494.

 

Gill, HS (1986). Kinetics of mast cell, basophil and eosinophil populations at Hyalomma anatolicum anatolicum feeding sites on cattle and the acquisition of resistance. Parasitology 93, 305–315.

 

Gill, HS and Walker, AR (1985). Differential cellular responses at Hyalomma anatolicum anatolicum feeding sites on susceptible and tick-resistant rabbits. Parasitology 91, 591-607.

 

Goldman, L; Johnson, P and Ramsay, J (1952). The insect bite reaction: I. The mechanism. Journal of Investigative Dermatology 18, 403-417.

 

Gonzalez-Acuña, DA and Guglielmone, AA (2005). Ticks (Acari: Ixodidae: Argasidae, Ixodidae) of Chile. Experimental and Applied Acarology 35,147–163.

 

Grigoreva, LA (2001). Histilogic changes of bird skin in feeding places of ticks of the genus Ixodes (Acari: Ixodidae). Parazitologia 35, 490-495.

 

Haag–Wackernagel, D and Bircher, AJ (2010). Ectoparasites from feral pigeons affecting humans. Dermatology 220, 82-92.

 

Haag–Wackernagel, D and Moch, H (2004). Health hazards posed by feral pigeons. Journal of Infection 48, 307-313.

 

Heijden, K; Szabo, M; Egami, M; Reira, M and Matushima, E (2005). Histopatology of tick-bite lesions in naturally infested capybaras (Hydrochoerus hydrochaeris) in Brazil. Experimental and Applied Acoralogy 37, 245-255.

 

Hilger, C; Bessot, JC; Hutt, N; Grigioni, F; Blay, F; Pauli, G and Hentges, F (2005). IgE-mediated anaphylaxis caused by sites of the pigeon tick Argas reflexus: cloning and expression of the major allergen Arg r1. Journal of Allergy and Clinical Immunology 115 , 617-622.

 

Hoogstraal, H (1985). Argasid and nuttalliellid ticks as parasites and vectors. Advances Parasitology 24, 135-238.

 

Jeffrey, G and Demain, MD (2003). Papular Urticaria and Things that Bite in the Night. Allergic Dermatosis and Urticaria 3, 291–303.

 

Kain, KC (1999). Skin lesions in returned travelers. Travel Medicine 83,1077-1102.

 

Kleine-Tebb, J; Herold, D; Dautel, H; Vater, G; Heinatz, A; Schroder, I; Haut, A; Mittag, T; Lange, I; Rytter, M and Haustein, UF (1999). The Pigeon Tick (Argas reflexus): Zentralblatt for Severe Allergic Bite Reactions in Humans. Zentbl Bakteriology 289, 754-755.

 

Kleine-Tebbe, J; Heinatz, A; Graser, I; Dautel, H; Hansen, GN; Kespohl, S; Rihs, HP; Raulf-Heimsoth, M; Vater, G; RyHer, M and Haustein, UF (2006). Bites of the European pigeon tick (Argas reflexus): Risk of IgE-mediated sensitizations and anaphylactic reactions. Journal of Allergy and Clinical Immunology 117, 190-195.

 

Kleine-Tebbe, J; Heinatz, A; Schroder, I; Dautel, H; Nordskov-Hansen, G and Haustein, UF (1998). Positive skin prick tests (SPT) and specific IgE (sIgE) to allergens of the pigeon tick (Argas reflexus) in patients with local and/or systemic bite reactions. Journal of Allergy and Clinical Immunology 101, S159.

Klotz, JH; Klotz, SA and Pinnas, JL (2009). Animal bites and stings with anaphylactic potential. Journal of Emergency Medicine 36, 148-156.

 

Kopecky, J and Kuthejlov, M (1998). Suppressive effect of Ixodes ricinus salivary gland extract on mechanisms of natural immunity in vitro. Parasite Immunology 20, 169–174.

 

Kopecky, J; Kuthejlov, M and Pechov, J (1999). Salivary gland extract from Ixodes ricinus ticks inhibits production of interferon-γ by the upregulation of interleukin-10. Parasite Immunology 21, 351–356.

 

Kovar, L (2004). Tick Saliva in Anti-Tick Immunity and Pathogen Transmission. Folia Microbiology 49, 327–336.

 

Kovar, L; Kopecky, J and Rihova, B (2002). Salivary gland extract from Ixodes ricinus tick modulates the host immune response towards the TH2 cytokine profile. Parasitology Research 88, 1066–1072.

 

Krinsky, WL (1983). Dermatoses associated with the bites of mites and ticks (Arthropoda: Acari). International Journal of Dermatology 22, 75-91.

 

Kubes, M; Fucsberger, N; Labuda, M; Zuffov, E and Nuttal, PA (1994). Salivary gland extracts of partially fed Dermacentor reticulates ticks decrease natural killer cell activity in vitro. Immunology 82, 113–116.

 

Kubes, M; Kopecky, P; Slovk, M; Slavkov, M; Fuchsber, N and Nuttall, PA (2002). Heterogeneity in the effect of different ixodid tick species on human natural killer cell activity. Parasite Immunology 24, 23–28.

 

Latif, AA; Maina, JN; Dhadialla, TS and Nokoe, S (1990). Histological reactions to bites of Amblyomma variagatum and Rhipicephalus appendicalatus (Acari; Ixodidae) fed simultaneously on naïve or sensitized rabbits. Journal of Medical Entomology 27, 316-323.

 

Latif, AA; Punyau, DK; Capstick, PB; Nokoe, S; Walker, AR and Fletcher, JD (1991). Histopathology of attachment sites of Amblyomma veriegatum and Rhipicephalus appendicalatus on Zebu cattle of varying resistance to ticks. Veterinary Parasitology 38, 505-513.

 

Lima, MF; Szabo, MP and Bechara, GH (2004). Microscopic features of tick-bite lesions in anteaters and armadillos: Emas National Park and the Pantanal region of Brazil. Annals of the New York Academy Sciences 1026, 235-241.

 

Mans, BJ; Andersen, JF; Schwan, TG and Ribeiro, JMC (2008). Characterization of anti-hemostatic factors in the argasid, Space Argas monolakensis: Implications for the evolution of blood-feeding in the soft tick family. Insect Biochemistry and Molecular Biology 38, 22–41.

 

Marshall, J (1967). Ticks and the human skin. Dermatologica 135, 60-65.

 

McGinley-Smith, DE and Tsao, SS (2003). Dermatoses from ticks. Journal of American Academy Medical Dermatology 49, 363-392.

 

Mclaren, DJ; Worms, MJ; Brown, SJ and Askenase, PW (1983). Ornithodorus tartakovskyi: quantitation, ultrastructure of cutaneous basophil reponses in the guinea pig. Experimental Parasitology 56, 153-168.

 

Miadonna, A; Tedeschi, A; Leggieri, E; Falagiani, P; Nazzari, M; Manzoni, M and Zanussi, C (1982). Anaphylactic shock caused by allergy to the venom of Argas reflexus. Annals of Allergy, Asthma and Immunology 49, 293–294.

 

Montasser, AA; Marzouk, AS; El-Alfy, SH and Baioumy, AA (2011). Efficacy of abamectin against the fowl tick, Argas (Persicargas) persicus (Oken, 1818) (Ixodoidea: Argasidae). Parasitology Research 109, 1113-1123.

 

Oleaga, A; Escudero-Poblacion, A; Camafeita, E and Perez-Sanchez, R (2007). A proteomic approach to the identification of salivary proteins from the argasid ticks Ornithodoros moubata and Ornithodoros erraticus. Insect Biochemistry and Molecular Biology 37, 1149–1159.

 

Pearce, RL and Grove, DI (1987). Tick infestation in soldiers who were bivouacked in the Perth region. Medical Journal of Australia 146, 238-240.

 

Ramachandra, RN and Wikel, SK (1992). Modulation of host-immune responses by ticks (Acari: Ixodidae): effect of salivary gland extracts on host macrophages and lymphocyte cytokine production. Journal of Medical Entomology 29, 818–826.

 

Ribeiro, JM; Makoul, GT; Levine, J; Robinson, DR and Spielman, A (1985). Antihemostatic, antiinflammatory, and immunosuppressive properties of the saliva of a tick, Ixodes dammini. Journal of Experimental Medicine 161, 332–344.

 

Ribeiro, JM; Weis, JJ and Telford, SR (1990). Saliva of the tick Ixodes dammini inhibits neutrophil function. Experimental Parasitology 70, 382–388.

 

Riek, RF and Lavoipierre, MMJ (1954). Reaction of the skin of laboratory animals to the bites of argasid ticks. Transactions of the Royal Society of Tropical Medicine and Hygiene 48, 8-9.

 

Roman, E; Battesti, MR and Charret, J (1960). Parasitisme chez un nourrisson de larves hexapodes de l’acarien Argas reflexus. Bulletin de la Societe de Pathologie Exotique Filiales 53, 420–423.

 

Russell FE (1974): Dermatitis due to imbedded tick parts. JAMA 228, 1581.

 

Sonenshine, DE (1991). Biology of Ticks, Vol 1. New York: Oxford University Press, pp.134-145.

 

Spiewak, R; Szostak, W; Kubicka, K; Ciura, D; Lundberg, M and Johansson, SGO (2004). An ‘‘endemic’’ of allergy to pigeon ticks (Argas reflexus) after removal of dovecotes. In: Abstract book of the XXIII EAACI Congress. Msterdam. European Academy of Allergology and Clinical Immunology. Van Wijk RG; Frew AJ; de Groot H; Kapsenberg M; de Monchy J and Van Ufford AQ (eds)., p.157.

 

Spiewak, R; Lundberg, M; Johansson, G and Buczek, A (2006). Allergy to pigeon tick (Argas reflexus) in Upper Silesia, Poland. Annals of Agriculture and Environmental Medicine 13, 107-112.

 

Stefanato, CM; Phelps, RG; Goldberg, LJ; Perry, AE and Bhawan, J (2001). Type-I cryoglobulinemia-like histopathologic changes in tick bites: a useful clue for tissue diagnosis in the absence of tick parts. Journal of Cutaneous Pathology 29, 101-116.

 

Szabo, MPJ and Bechara, GH (1999). Sequential histopathology at the Rhipicephalus sanguineus tick feeding site on dogs and guinea pigs. Experimental and Applied Acarology 23, 915–928.

 

Tavassoli, E; Zare, S; Ghaderi, F; Tehrani, AA and Tavassoli, M (2007). Histopatological feauturers of Ornithodoros lahorensis bite on rat. Iranian Journal of parasitology 2 (4), 17-24.

 

Tavassoli, M; Pourseyed, SH; Ownagh, A; Bernousi, I and Mardani, K (2011). Biocontrol of pigeon tick Argas reflexus(Acari:Argasidae) by entomophatogenic fungus Metarhizium anisopliae (ascomycota: Hypocreales). British Medical Journal 42, 1445-1452.

 

Trautmann, A; Amschler, A; Schultz, KD; Brecker, EB and Klein, CE (1995). Anaphylactic reactions caused by pigeon ticks. Dermatosen 43, 215-218.

 

Urioste, S; Hall, LR; Telford, SR and Titus, RG (1994). Saliva of the Lyme disease vector, Ixodes dammini, blocks cell activation by a nonprostaglandin E2-dependent mechanism. Journal of Experimental Medicine 180, 1077–1085.

 

Uspensky, I (2008). Argasid (soft) Ticks (Acari: Ixodida: Argasidae). In: Encyclopedia of parasitology, Mehlborn H (ed),. 3rd Edition, Springer Publishing Co., pp. 283-287.

 

Venzal, JM; Estrada-Pena, A and Fernandez-Deluco, D (2007). Effects produced by the feeding of larvae of ornithodoros aff.puertoricensis (Acari: Argazidae) on laboratory mice. Experimental and Applied Acoralogy 42, 217-223.

 

Veronez, VA; Castro, MB; Bechara, GH and Szabo, MPJ (2010). Histopathology of Rhipicephalus sanguineus (Acari: Ixodidae) ticks fed on resistant hosts. Experimental and Applied Acarology 50, 151–161.

 

Wall, R and Shearer, D (1997). Veterinary Entomology, 1st ed. Chapman and Hall International Thompson Publisher Company, London.

 

Weckesser, S; Hilger, C; Lentz, D and Jakob, T (2010). Anaphylactic reactions to bites of the pigeon tick Argas reflexus. European Journal of Dermatology 20, 244-245.

 

Wikel, SK (1982): Immune responses to arthropod and their products. Annual Review of Entomology 27, 21–48.

 

Yesudian, P and Thambiah, AS (1973). Persistent papules after tick-bites. Dermatologica 147, 214-218.