Preparation of a Bilayer Coating of nHydroxyapatite/Poly(lactic-co-glycolic)acid on Mg and Investigation of Corrosion Properties and Biocompatibility

مهندسی متالورژی و مواد

Article 3, Volume 35, Issue 3 - Serial Number 35, October 2024, Pages 35-50   

Document Type: Original Articles

DOI: 10.22067/jmme.2024.83920.1121

Authors

Neda Aboudzadeh^* ; Mina Mohamadizadeh; Alireza Khavandi; alireza eivani

School of Metallurgy and Materials Engineering, Iran University of science and Technology, Tehran, Iran.

Abstract

In this study, intending to control the corrosion of magnesium and its clinical application, a double-layer coating of Hydroxyapatite- Poly lactic-co-glycolic acid was applied on Mg by means of the electrodeposition and the dip method, respectively. X-ray diffraction (XRD) and scanning electron microscopy (SEM) are used to characterize the phase and morphology of the coatings. The results show a homogeneous coating with a thickness of 20-30 µm. Potentiodynamic polarization of the samples revealed that the double-layer coating exhibited a significant increase in corrosion potential, ranging from -1.82 to -1.4 V, and a decrease in corrosion current, ranging from 2.3 to 0.37 µA/cm2. Moreover, the MTT assay of the samples revealed that the amount of cell proliferation in the vicinity of the 48-hour extract of magnesium samples with double-layer coating had increased, indicating a decrease in the amount of ions released from the surface of magnesium by applying this coating.

Keywords

Magnesium; Hydroxyapatite; Poly lactic-co-glycolic acid; Double-layer coating; Corrosion; Biocompatibility

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