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The pluripotency feature of cancer cells; product of a harmony or an output of a disharmony | ||
Journal of Cell and Molecular Research | ||
مقاله 1، دوره 6، شماره 2 - شماره پیاپی 12، فروردین 2014، صفحه 50-51 اصل مقاله (22.95 K) | ||
نوع مقاله: Editorial | ||
شناسه دیجیتال (DOI): 10.22067/jcmr.v6i2.32838 | ||
نویسنده | ||
Hesam Dehghani* | ||
Ferdowsi University of Mashhad | ||
چکیده | ||
Pluripotency is a central feature of stem and cancer cells. This feature enables cancer cells to self-renew and trans-differentiate. In this editorial, it is hypothesized that in cancer cells synchronized events rather than segmented procedures may lead to pluripotency. | ||
کلیدواژهها | ||
pluripotency؛ Stem cells؛ Cancer cells | ||
مراجع | ||
Dehghani H., Dellaire G. and Bazett-Jones D.P. (2005) Organization of chromatin in the interphase mammalian cell. Micron 36(2): p. 95-108.
Efroni S., et al. (2008) Global transcription in pluripotent embryonic stem cells. Cell Stem Cell 2(5): p. 437-47.
Gaspar-Maia A., et al.(2011) Open chromatin in pluripotency and reprogramming. Nature Reviews Molecular Cell Biology,. 12(1): p. 36-47.
Apostolou P., et al.(2012) Cancer stem cells stemness transcription factors expression correlates with breast cancer disease stage. Current Stem Cell Research Therapy 7(6): p. 415-9.
Liu A., Yu X. and Liu S. (2013) Pluripotency transcription factors and cancer stem cells: small genes make a big difference. Clinical Journal of Cancer 32(9): p. 483-7.
Hann S. R. (2014) MYC Cofactors: Molecular Switches Controlling Diverse Biological Outcomes. Cold Spring Harb Perspect Med.
Hurlin P.J., (2013) Control of vertebrate development by MYC. Cold Spring HarbPerspect Med,. 3(9): p. a014332.
Hirasaki M., et al., (2013) Striking similarity in the gene expression levels of individual Myc module members among ESCs, EpiSCs, and partial iPSCs. PLoS One 8(12): p. e83769.
Chappell J. and DaltonS. (2013) Roles for MYC in the establishment and maintenance of pluripotency. Cold Spring HarbPerspect Med 3(12): p. a014381.
Shekhani M.T., et al.(2013) Cancer stem cells and tumor transdifferentiation: implications for novel therapeutic strategies. American Journal of Stem Cells 2(1): p. 52-61.
Barneda-Zahonero, B., et al. (2012) Epigenetic regulation of B lymphocyte differentiation, transdifferentiation, and reprogramming. Computer Functional Genomics 2012: p. 564381.
Sabe H., (2011) Cancer early dissemination: cancerous epithelial-mesenchymal transdifferentiation and transforming growth factor beta signalling. Journal of Biochemistry 149(6): p. 633-9. | ||
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