Molecular Interactions of lncRNAs: Cellular Fate Determination and Tissue Regeneration

Journal of Cell and Molecular Research

مقاله 1، دوره 7، شماره 2 - شماره پیاپی 14، اسفند 2015، صفحه 68-69   

نوع مقاله: Editorial

شناسه دیجیتال (DOI): 10.22067/jcmr.v7i2.40861

نویسندگان

Monireh Bahrami؛ Muhammad Irfan-Maqsood^*

Ferdowsi University of Mashhad

چکیده

LncRNAs (long non-coding RNAs) are responsible to control the degradation process, RNA stability, orchestration, inhibition, transcription and histone modification etc. These RNAs have been termed as the key agents of several mechanisms such as development, organogenesis and regeneration of damaged tissues etc. They interact with a number of partner molecules either protein, RNAs or DNAs and control the cellular behaviour while differentiation or maintaining the stem cell status. This editorial is discussing the significance of lncRNAs as therapeutic target in stem cell therapy field.

کلیدواژه‌ها

LncRNAs؛ Regeneration؛ Molecular interactions؛ Stem cell fate؛ Differentiation