MicroRNA-mediated resistance to plant viruses

Journal of Cell and Molecular Research

Article 1, Volume 10, Issue 1 - Serial Number 19, January 0, Pages 40-46   

Document Type: Review / Mini-Review

DOI: 10.22067/jcmr.v10i1.70766

Author

امین الله طهماسبی

دانشگاه شیراز

Abstract

MicroRNAs (miRNAs) are 20-24 nucleotide small RNAs which are processed from nuclear-encoded transcripts. miRNAs control the expression of target transcripts by cleaving or translational inhibition of the target RNAs. Artificial microRNAs (amiRNAs) are modified endogenous miRNA precursors in which the miRNA: miRNA duplex is replaced with sequences to silence a target gene. amiRNAs are used as new transformation techniques in eukaryotes and have been proven to be more effective in specificity and stability than other RNA-mediated gene silencing methods. amiRNA-based antiviral defense is an effective and new approach to engineer resistance to plant viruses. Here, we summarize the role of miRNAs in resistance to plant viruses.

Keywords

amiRNA; Gene silencing; miRNA; Plant viruses; Resistance

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