Immune response characteristics of Capri pox virus vaccines following emergency vaccination of cattle against lumpy skin disease virus

Iranian Journal of Veterinary Science and Technology

مقاله 5، دوره 9، شماره 2 - شماره پیاپی 17، 2017، صفحه 33-40   

نوع مقاله: Research Articles

شناسه دیجیتال (DOI): 10.22067/veterinary.v9i2.65381

نویسندگان

hamid Reza varshovi¹؛ Reza Norian^{* 2}؛ Abbas Azadmehr³؛ nahideh afzal ahangaran²

¹Razi Vaccine and Serum Research Institute

²Urmia University

³Babol University of Medical Sciences

چکیده

In this research immune response characteristics of two available heterologous vaccines including Gorgan goat pox virus (GPV) and Romanian sheep pox virus (SPV) vaccines against lumpy skin disease have been examined, by using the monitoring of humoral and cell-mediated immune responses in vaccinated calves in the field. The evaluation of humoral immune response showed that the neutralizing antibody titers in both vaccinated groups started at day 7 post-vaccination, then reached to the protective level at day 21 post-vaccination and persisted till 35 day post-vaccination. The neutralizing antibody titers in GPV-vaccinated calves (GVC) the ratio was higher than SPV-vaccinated calves (RVC), and on days 21 and 35 post-vaccination were significantly different (p

کلیدواژه‌ها

Goat Pox Virus؛ Sheep Pox Virus؛ Lumpy skin disease؛ IL-4؛ IFN-γ

مراجع