Reflexology, Foot massage, Chronic low back pain

Research in Exercise and Sports Medicine

دوره 3، شماره 2، بهمن 2012، صفحه 19-23   

نوع مقاله: Original Article

چکیده

Introduction: Visfatin is a newly discovered adipokine. Previous studies showed a direct relationship 
between plasma visfatin levels and type 2 diabetes mellitus (T2DM). The current study was conducted to 
investigate the effect of aerobic exercise on plasma visfatin in type 2 diabetic men treated with metformin.
Material and Methods: Thirty-six men with type 2 diabetes who consumed metformin (age 46/08 ± 3/08 
years, BMI 30/1± 2/32 kg/m2
, mean ± SD) volunteered to participate in this study. Subjects were randomly 
assigned in 2 groups. 18 subjects were in the aerobic exercise group (3 days per week, 35 to 50 minutes per 
day, 40-55% heart rate reserve) and 18 subjects in the control group. Fasting Plasma visfatin, insulin and 
glucose concentrations were measured before and after 8 weeks exercise in patients with T2DM and data was 
analyzed using Repeated Measures (ANOVA) at a Significance level of (P<0.05).
Results: The results showed that plasma visfatin levels, insulin, glucose, BMI, WHR and body fat 
percentage significantly decreased in aerobic exercise group compared with control group (p<0.05). The peak 
rate of oxygen consumption (vo2peak) significantly increased in aerobic exercise group compared to control 
group (p<0.05).
Discussion and Conclusion: The present study showed decrease of plasma visfatin induced by aerobic 
exercise is most likely the result of improving glycemic control in patients with T2DM treated with metformin. 

کلیدواژه‌ها

Aerobic exercise؛ Visfatin؛ metformin؛ Type 2 diabetes