تأثیر نسبت‌های مختلف متیونین- روی و اکسید روی بر شاخص‌های عملکردی و اسهال گوساله‌های شیرخوار هلشتاین

پژوهشهای علوم دامی ایران

مقاله 1، دوره 16، شماره 3 - شماره پیاپی 59، مهر 1403، صفحه 317-330   

نوع مقاله: مقاله پژوهشی

شناسه دیجیتال (DOI): 10.22067/ijasr.2024.83930.1168

نویسندگان

مرتضی رضاپور؛ یداله چاشنی دل^* ؛ اسداله تیموری یانسری؛ عیسی دیرنده

گروه علوم دامی، دانشکده علوم دامی و شیلات، دانشگاه علوم کشاورزی و منابع طبیعی ساری، ساری، ایران

چکیده

اسهال، یکی از عوامل اصلی مرگ ‌و میر گوساله­ها در دو هفته اول پس از تولد است، بنابراین شناسایی ترکیبات مؤثر بر پیشگیری از اسهال برای گوساله­های شیرخوار، بسیار مهم است. به­منظور بررسی نسبت­های مختلف مکمل­های روی بر بهبود اسهال و عملکرد گوساله­ها، تعداد 50 راس گوساله هلشتاین شیرخوار در قالب یک طرح کاملاً تصادفی با پنج تیمار و 10 تکرار استفاده شد. تیمارهای آزمایشی شامل مصرف مکمل روی به‌صورت 1) 100درصد متیونین- روی، 2) 75 درصد متیونین- روی و 25 درصد اکسید روی، 3) 50 درصد متیونین- روی و 50 درصد اکسید روی، 4) 25 درصد متیونین- روی و 75 درصد اکسید روی و 5) 100 درصد اکسید روی بود. مکمل روی از روز اول تولد تا روز 14 به گوساله­ها تغذیه شد و بررسی عملکرد به‌مدت 70 روز تا زمان قطع شیر ادامه داشت. ماده خشک مصرفی، افزایش وزن روزانه و امتیاز قوام مدفوع گوساله­ها تحت تأثیر تیمارهای آزمایشی قرار نگرفت. نسبت­های بالاتر اکسید روی سبب کاهش معنی‌دار غلظت آلکالین فسفاتاز و سوپراکسید دیسموتاز خون در روز 14 و 70 آزمایش شد. همچنین در روز 70 آزمایش، ظرفیت آنتی‌اکسیدانی کل خون، در تیمارهای حاوی متیونین- روی، به‌طور معنی­داری بیشتر از تیمار 5 (100 درصد اکسید روی) بود. در مجموع، عملکرد تولیدی، در نسبت­های مختلف منبع آلی و معدنی تغییر نکرد، عدم تأثیر جایگزینی اکسید روی با متیونین- روی بر عملکرد گوساله­ها در مطالعه حاضر ممکن است به‌دلیل ارائه سطوح کافی روی برای همه گوساله­ها باشد. بنابراین می­توان بیان داشت، در زمانی که عنصر روی در سطح کافی تأمین ­شود، شکل شیمیایی و زیست‌فراهمی منابع دارای اهمیت کمتری هستند.

کلیدواژه‌ها

اسهال؛ اکسید روی؛ سیستم ایمنی؛ گوساله شیرخوار؛ متیونین روی

مراجع

1. Abdollahi, M., Rezaei, J., & Fazaeli, H. (2020). Performance, rumen fermentation, blood minerals, leukocyte and antioxidant capacity of young Holstein calves receiving high-surface ZnO instead of common ZnO. Archives of Animal Nutrition, 74(3), 189-205. https://doi.org/10.1080/1745039x.2019.1690389
2. Adab, M., Mahjoubi, E., Yazdi, M. H., & Collier, R. J. (2020). Effect of supplemental dietary Zinc and its time of inclusion on pre-weaning phase of Holstein heifer calves: Growth performance and health status. Livestock Science, 231, 103891. https://doi.org/10.1016/j.livsci.2019.103891
3. Alimohamady, R., Aliarabi, H., Bruckmaier, R. M., & Christensen, R. G. (2019). Effect of different sources of supplemental zinc on performance, nutrient digestibility, and antioxidant enzyme activities in lambs. Biological Trace Element Research, 189(1), 75-84. https://doi.org/10.1007/s12011-018-1448-1
4. Anil, T. S. V., Seshaiah, C. V., Ashalatha, P., & Sudhakar, K. S. (2020). Effect of dietary nano zinc oxide supplementation on haematological parameters, serum biochemical parameters and hepato-renal bio-markers in crossbred calves. International Journal of Current Microbiology and Applied Sciences, 9, 2034-2044.
5. Cani, P. D., Amar, J., Iglesias, M. A., Poggi, M., Knauf, C., Bastelica, D., Neyrinck, A. M., Fava, F., Tuohy, K. M., Chabo, C., Waget, A., Delmée, E., Cousin, B., Sulpice, T., Chamontin, B., Ferrières, J., Tanti, J. F., Gibson, G. R., Casteilla, L., Delzenne, N. M., Alessi, M. C., & Burcelin, R. (2007). Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes, 56(7), 1761-1772. https://doi.org/10.2337/db06-1491
6. Chang, M. N., Wei, J. Y., Hao, L. Y., Ma, F. T., Li, H. Y., Zhao, S. G., & Sun, P. (2020). Effects of different types of zinc supplement on the growth, incidence of diarrhea, immune function, and rectal microbiota of newborn dairy calves. Journal of Dairy Science, 103(7), 6100-6113. http://dx.doi.org/10.3168/jds.2019-17610
7. Cho, Y. E., Lomeda, R. A., Ryu, S. H., Sohn, H. Y., Shin, H. I., Beattie, J. H., & Kwun, I. S. (2007). Zinc deficiency negatively affects alkaline phosphatase and the concentration of Ca, Mg and P in rats. Nutrition Research and Practice, 1(2), 113-119. https://doi.org/10.4162/nrp.2007.1.2.113
8. Cho, Y. I., & Yoon, K. J. (2014). An overview of calf diarrhea - infectious etiology, diagnosis, and intervention. Journal of Veterinary Science, 15(1), 1-17. http://dx.doi.org/10.4142/jvs.2014.15.1.1
9. Cousins, R. J., Blanchard, R. K., Moore, J. B., Cui, L., Green, C. L., Liuzzi, J. P., Cao, J., & Bobo, J. A. (2003). Regulation of zinc metabolism and genomic outcomes. The Journal of Nutrition, 133(5 Suppl 1), 1521s-1526s. http://dx.doi.org/10.1093/jn/133.5.1521S
10. Feldmann, H. R., Williams, D. R., Champagne, J. D., Lehenbauer, T. W., & Aly, S. S. (2019). Effectiveness of zinc supplementation on diarrhea and average daily gain in pre-weaned dairy calves: A double-blind, block-randomized, placebo-controlled clinical trial. PLoS One, 14(7), e0219321. https://doi.org/10.1371/journal.pone.0219321
11. Genther, O. N., & Hansen, S. L. (2014). Effect of dietary trace mineral supplementation and a multi-element trace mineral injection on shipping response and growth performance of beef cattle. Journal of Animal Science, 92(6), 2522-2530. http://dx.doi.org/10.2527/jas.2013-7426
12. Glover, A. D., Puschner, B., Rossow, H. A., Lehenbauer, T. W., Champagne, J. D., Blanchard, P. C., & Aly, S. S. (2013). A double-blind block randomized clinical trial on the effect of zinc as a treatment for diarrhea in neonatal Holstein calves under natural challenge conditions. Prev Vet Med, 112(3-4), 338-347. http://dx.doi.org/10.1016/j.prevetmed.2013.09.001
13. Grešáková, Ľ., Tokarčíková, K., & Čobanová, K. (2021). Bioavailability of dietary zinc sources and their effect on mineral and antioxidant status in lambs. Agriculture, 11(11), 1093.
14. Hu, C. H., Xiao, K., Song, J., & Luan, Z. S. (2013). Effects of zinc oxide supported on zeolite on growth performance, intestinal microflora and permeability, and cytokines expression of weaned pigs. Animal Feed Science and Technology, 181, 65–71. http://dx.doi.org/10.1016/j.anifeedsci.2013.02.003
15. Jia, W., Zhu, X., Zhang, W., Cheng, J., Guo, C., & Jia, Z. (2009). Effects of source of supplemental zinc on performance, nutrient digestibility and plasma mineral profile in Cashmere goats. Asian-australasian Journal of Animal Sciences, 22, 1648-1653.
16. Jing, M. Y., Sun, J. Y., & Wang, J. F. (2008). The effect of peripheral administration of zinc on food intake in rats fed Zn-adequate or Zn-deficient diets. Biological Trace Element Research, 124(2), 144-156. http://dx.doi.org/10.1007/s12011-008-8132-9
17. Kumar, A., Sahu, D., Chandra, G., Yadav, S. P., Kumar, R., Jaiswal, V., Maurya, P., & Singh, R. K. (2018). Effect of different sources of zinc on growth performance and haemato-biochemical profiles of Murrah Buffalo calves. Indian Journal of Animal Nutrition, 35, 409. http://dx.doi.org/10.5958/2231-6744.2018.00062.2
18. Kwun, I. S., Cho, Y. E., Lomeda, R. A., Kwon, S. T., Kim, Y., & Beattie, J. H. (2007). Marginal zinc deficiency in rats decreases leptin expression independently of food intake and corticotrophin-releasing hormone in relation to food intake. The British Journal of Nutrition, 98(3), 485-489. http://dx.doi.org/10.1017/s0007114507730763
19. Li, Y., & Maret, W. (2009). Transient fluctuations of intracellular zinc ions in cell proliferation. Experimental Cell Research, 315(14), 2463-2470. http://dx.doi.org/10.1016/j.yexcr.2009.05.016
20. Ma, F., Wo, Y., Li, H., Chang, M., Wei, J., Zhao, S., & Sun, P. (2020). Effect of the source of zinc on the tissue accumulation of zinc and jejunal mucosal zinc transporter expression in Holstein dairy calves. Animals (Basel), 10(8). http://dx.doi.org/10.3390/ani10081246
21. Mallaki, M., Norouzian, M., & Khadem, A. (2015). Effect of organic zinc supplementation on growth, nutrient utilization,and plasma zinc status in lambs. Turkish Journal of Veterinary and Animal Sciences, 39, 75-80. http://dx.doi.org/10.3906/vet-1405-79
22. Mandal, G. P., Dass, R., Isore, D. P., Garg, A., & Ram, G. (2007). Effect of zinc supplementation from two sources on growth, nutrient utilization and immune response in male crossbred cattle (Bos indicus X Bos taurus) bulls. Animal Feed Science and Technology, 138, 1-12. http://dx.doi.org/10.1016/j.anifeedsci.2006.09.014
23. Marcondes, M., Pereira, T., Chagas, J., Filgueiras, E., Castro, D. M., Costa, G., Sguizzato, A., & Sainz, R. (2016). Performance and health of Holstein calves fed different levels of milk fortified with symbiotic complex containing pre- and probiotics. Tropical Animal Health and Production, 48. http://dx.doi.org/10.1007/s11250-016-1127-1
24. Mattioli, G. A., Rosa, D. E., Turic, E., Relling, A. E., Galarza, E., & Fazzio, L. E. (2018). Effects of copper and zinc supplementation on weight gain and hematological parameters in pre-weaning calves. Biological trace element research, 185(2), 327-331. http://dx.doi.org/10.1007/s12011-017-1239-0
25. Miller, N. J., Rice-Evans, C., Davies, M. J., Gopinathan, V., & Milner, A. (1993). A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clinical Science (Lond), 84(4), 407-412. http://dx.doi.org/10.1042/cs0840407
26. Najafzadeh, H., Ghoreishi, S., Mohammadian, B., Rahimi, E., Afzalzadeh, M., Kazemivarnamkhasti, M., & Ganjealidarani, H. (2013). Serum biochemical and histopathological changes in liver and kidney in lambs after zinc oxide nanoparticles administration. Veterinary World, 6, 534. http://dx.doi.org/10.5455/vetworld.2013.534-537
27. Nayeri, A., Upah, N. C., Sucu, E., Sanz-Fernandez, M. V., DeFrain, J. M., Gorden, P. J., & Baumgard, L. H. (2014). Effect of the ratio of zinc amino acid complex to zinc sulfate on the performance of Holstein cows. Journal of Dairy Science, 97(7), 4392-4404. http://dx.doi.org/10.3168/jds.2013-7541
28. Paglia, D. E., & Valentine, W. N. (1967). Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. Journal of Laboratory and Clinical Medicine, 70(1), 158-169.
29. Patel, B., Kumar, N., Kotresh Prasad, C., Rajpoot, V., & Lathwal, S. S. (2021). Effect of zinc supplementation on physiological and oxidative stress status of peri-parturient Karan Fries cows during heat stress condition. Journal of Entomology and Zoology Studies, 9, 4.
30. Sales, J. (2013). Effects of pharmacological concentrations of dietary zinc oxide on growth of post-weaning pigs: a meta-analysis. Biological Trace Element Research, 152(3), 343-349. http://dx.doi.org/10.1007/s12011-013-9638-3
31. Santman-Berends, I., de Bont-Smolenaars, A. J. G., Roos, L., Velthuis, A. G. J., & van Schaik, G. (2018). Using routinely collected data to evaluate risk factors for mortality of veal calves. Preventive Veterinary Medicine, 157, 86-93. http://dx.doi.org/10.1016/j.prevetmed.2018.05.013
32. Schulte, J. N., Brockmann, G. A., & Kreuzer-Redmer, S. (2016). Feeding a high dosage of zinc oxide affects suppressor of cytokine gene expression in Salmonella typhimurium infected piglets. Veterinary Immunology and Immunopathology, 178, 10-13. http://dx.doi.org/10.1016/j.vetimm.2016.06.009
33. Seifdavati, J., Jahan Ara, M., Seyfzadeh, S., Abdi Benamar, H., Mirzaei Aghjehgheshlagh, F., Seyedsharifi, R., & Vahedi, V. (2018). The Effects of zinc oxide nano particles on growth performance and blood metabolites and some serum enzymes in Holstein suckling calves. . Iranian Journal of Animal Science Research, 10(1), 11. (In Persian).http://dx.doi.org/10.22067/ijasr.v10i1.62376.
34. Shanigaram, P., Nagalakshmi, D., & Kumar, K. (2015). Effect of zinc supplementation on haematology and serum biochemical constituents in Murrah buffalo calves. Indian Journal of Animal Research, 49, 482. http://dx.doi.org/10.5958/0976-0555.2015.00095.3
35. Shen, J., Chen, Y., Wang, Z., Zhou, A., He, M., Mao, L., Zou, H., Peng, Q., Xue, B., Wang, L., Zhang, X., Wu, S., & Lv, Y. (2014). Coated zinc oxide improves intestinal immunity function and regulates microbiota composition in weaned piglets. The British Journal of Nutrition, 111(12), 2123-2134. http://dx.doi.org/10.1017/s0007114514000300
36. Shen, X., Song, C., & Wu, T. (2021). Effects of nano-copper on antioxidant function in copper-deprived guizhou black goats. Biological Trace Element Research, 199(6), 2201-2207. http://dx.doi.org/10.1007/s12011-020-02342-1
37. Soufi, B., Alijoo, Y. A., Khamisabadi, H., & Khoobbakht, Z. (2022). The effect of inorganic, organic and nano-zinc sources on growth performance, blood parameters and antioxidant activity of Sanjabi lambs. Journal of Ruminant Research, 9(4), 19-32.
38. Spears, J. W., & Weiss, W. P. (2008). Role of antioxidants and trace elements in health and immunity of transition dairy cows. The Veterinary Journal, 176(1), 70-76. http://dx.doi.org/10.1016/j.tvjl.2007.12.015
39. Suttle, N. F. (2010). Mineral Nutrition of Livestock. 4^th Wallingford, Oxfordshire, CABI
40. Teixeira, A. G., Stephens, L., Divers, T. J., Stokol, T., & Bicalho, R. C. (2015). Effect of crofelemer extract on severity and consistency of experimentally induced enterotoxigenic Escherichia coli diarrhea in newborn Holstein calves. Journal of Dairy Science, 98(11), 8035-8043. http://dx.doi.org/10.3168/jds.2015-9513
41. Ulutaş, E., Eryavuz, A., Bülbül, A., Rahman, A., Küçükkurt, İ., & Uyarlar, C. (2020). Effect of zinc supplementation on haematological parameters, biochemical components of blood and rumen fluid, and accumulation of zinc in different organs of goats. Pakistan Journal of Zoology, 52. http://dx.doi.org/10.17582/journal.pjz/20190603230641
42. Wang, B., Yang, C. T., Diao, Q. Y., & Tu, Y. (2018). The influence of mulberry leaf flavonoids and Candida tropicalis on antioxidant function and gastrointestinal development of preweaning calves challenged with Escherichia coli O141:K99. Journal of Dairy Scienc, 101(7), 6098-6108. http://dx.doi.org/10.3168/jds.2017-13957
43. Wei, J., Ma, F., Hao, L., Shan, Q., & Sun, P. (2019). Effect of differing amounts of zinc oxide supplementation on the antioxidant status and zinc metabolism in newborn dairy calves. Livestock Science, 230, 103819. http://dx.doi.org/10.1016/j.livsci.2019.103819
44. Zaboli, K., Aliarabi, H., Bahari, A., & Abbasalipourkabir, R. (2013). Role of dietary nano-zinc oxide on growth performance and blood levels of mineral: A study on Iranian Angora (Markhoz) goat kids. Journal of Pharmaceutical and Health Science, 2(1), 19-26.