Effects of industrial wastewater on gross and histopathological changes of vital organs of Swiss albino mice

Iranian Journal of Veterinary Science and Technology

مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 13 اردیبهشت 1404   

نوع مقاله: Research Article

شناسه دیجیتال (DOI): 10.22067/ijvst.2025.89087.1402

نویسندگان

Md. Taimur Islam^{* 1}؛ Mohosina Mou²؛ Nusrat Binte Rafique²؛ Robius Sani Sadi¹؛ Md. Selim Jahangir Saurov¹؛ Anup Kumar Talukder³؛ Ziban Chandra Das³؛ Minhaz Ahmed⁴؛ Md. Golam Haider⁵

¹Department of Pathobiology, Faculty of Veterinary Medicine and Animal Science, Gazipur Agricultural University, Gazipur-1706, Bangladesh

²Department of Pathobiology, Faculty of Veterinary Medicine and Animal Science, Gazipur Agricultural University, Gazipur 1706, Bangladesh

³Department of Gynecology, Obstetrics and Reproductive Health, Faculty of Veterinary Medicine and Animal Science, Gazipur Agricultural University, Gazipur 1706, Bangladesh

⁴Department of Agroforestry and Environment, Faculty of Forestry and Environment, Gazipur Agricultural University, Gazipur 1706, Bangladesh

⁵Department of Pathobiology, Faculty of Veterinary Medicine and Animal Science, Gazipur Agricultural University, Gazipur, 1706, Bangladesh.

چکیده

Industrial wastewater contaminates the land, water, and air, causing serious environmental damage. Industrial wastewater can be combustible, reactive, poisonous, or carcinogenic. Therefore, this study was aimed to investigate the effects of industrial wastewater on the growth, and gross and histoarchitecture of vital organs of male Swiss albino mice. Thirty-two mice of four weeks of age were divided into four groups. Normal drinking water was supplied to the control group of mice. Mice of groups 1, 2 and 3 were supplied normal drinking water mixed with garments industrial wastewater at 5%, 10% and 20% concentrations, respectively orally up to experimental week 24. After completing 24 weeks of treatment of mice with different concentrations of industrial wastewater, body weight of mice, and weight of liver, heart and kidney of mice were measured. Moreover, histopathological changes in liver, heart and kidney were investigated. Body weight was decreased in wastewater treated mice in comparison to control mice. Weight of liver of wastewater treated mice were increased. Nevertheless, weight of hearts and kidneys were decreased in wastewater treated mice. Congestion, hepatocellular necrosis and infiltration of inflammatory cells were observed in liver. Disruption of connective tissue were evident in myocardium of heart of wastewater treated mice with necrosis and infiltration of inflammatory cells. Moreover, congestion, cellular necrosis, hypertrophied glomerulus, degeneration in renal tubular epithelial cells, and dilated tubules were evident in kidney. From these findings, it was concluded that industrial wastewater has detrimental effects on the vital organs of mice.

کلیدواژه‌ها

Industrial wastewater؛ histopathology؛ heart؛ kidney؛ liver